|
KMID : 0378019790220020074
|
|
New Medical Journal
1979 Volume.22 No. 2 p.74 ~ p.82
|
|
|
Serum Complement in Patients with Cancer
|
|
權仁順/Kwon, In Soon
朴正植/金聖權/李正相/金丁龍/李文鎬/Park, Jung Sik/Kim, Sung Kwon/Lee, Jung Song/Kim, Jung Yong/Lee, Munho
|
|
|
Abstract
|
|
|
Awareness that advancing cancer is accompanied by defective immunologic responses, and accumulating evidence that, immune reactions may influence the. course of cancer, has stimulated the study of various mechanisms of immunologic reaction in patients with cancer.
The role of antibody and complement in several cytotoxic and cytocidal system is well established. Considering that serum complement is 5-5% of serum -protein, there are many trial to explain the immune reaction by measuring serum complement, but no definite concepts.
Our results are as follows.
1. Comparing the mean value of C3 and C4 in 102 cancer patients with normal individuals, there are significantly decreased C3 and significantly increased C4 value in patients with cancer (P<0.01) .
2. Number of patients in group C3 : ↓C4 : N, and C3 : N C4 : T were increased with abnormal distribution.
3. There was no follow up in stomach and colon cancer patients. The hospital admission period and follow up of hepatoma patients was longer, we could see 6 deaths. 5 deaths were in group C3 : J. C4 : N and 4 of them were expired within 1 week after test. 1 death was group C3 : N C4 : T . During observation period, we could see his complement values were decreasing with resultant death.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|
|